Barbiturates such as pentobarbitals and phenobarbitals,are central nervous system (CNS) depresssants,thes were used as anxiolytics,hypnotics and anti convulsion agents.Barbiturates may be taken intravenously or evn orally.The use of barbiturates produce a wide spectrum of effects;like slowing of speech,fatigue and anesthesia.Abuse of barbiturates can lead to mental disorder,impaired motor coordination,respiratory failure,coma and even death.Chronic use of barbiturates can lead to physical dependence,the most commonly abused barbiturates are amobarbital,pentobarbital and Secobarbital.Short-acting barbiturated like secobarbital have a half life of 29 to 34 hours and will generally be excreted in urine as metabolites while long acting barbitals like phenobarbitals have a half life of 24 to 140 hrs. and will primarily appear unchanged. This test detects the presence of Barbiturates in human urine specimen,qualitatively.